The only true medically effective way to consume marijuana is sublingually. Other wise it doesn't pass the blood brain barrier. THC may have hormonal consequences in that it stimulates the opposite effect based on your gender. Males produce more estrogen and in Females it tends to do the opposite stimulating the testosterone hormone. you usually look for a full spectrum sublingual thats a minimum of 1to2 ratio THC to CBD. taking on average 10ml to every 5kg of weight. When you get down to the financial aspect of it. It can be quite a pricy treatment protocol as you can imagine.